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A fat-tissue sensor couples growth to oxygen availability by remotely controlling insulin secretion
Organisms adapt their metabolism and growth to the availability of nutrients and oxygen, which are essential for development, yet the mechanisms by which this adaptation occurs are not fully understood. Here we describe an RNAi-based body-size screen in Drosophila to identify such mechanisms. Among...
Autores principales: | Texada, Michael J., Jørgensen, Anne F., Christensen, Christian F., Koyama, Takashi, Malita, Alina, Smith, Daniel K., Marple, Dylan F. M., Danielsen, E. Thomas, Petersen, Sine K., Hansen, Jakob L., Halberg, Kenneth A., Rewitz, Kim F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486587/ https://www.ncbi.nlm.nih.gov/pubmed/31028268 http://dx.doi.org/10.1038/s41467-019-09943-y |
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