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Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

ABC toxins are pore-forming virulence factors produced by pathogenic bacteria. YenTcA is the pore-forming and membrane binding A subunit of the ABC toxin YenTc, produced by the insect pathogen Yersinia entomophaga. Here we present cryo-EM structures of YenTcA, purified from the native source. The so...

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Detalles Bibliográficos
Autores principales: Piper, Sarah J, Brillault, Lou, Rothnagel, Rosalba, Croll, Tristan I, Box, Joseph K, Chassagnon, Irene, Scherer, Sebastian, Goldie, Kenneth N, Jones, Sandra A, Schepers, Femke, Hartley-Tassell, Lauren, Ve, Thomas, Busby, Jason N, Dalziel, Julie E, Lott, J Shaun, Hankamer, Ben, Stahlberg, Henning, Hurst, Mark R H, Landsberg, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486591/
https://www.ncbi.nlm.nih.gov/pubmed/31028251
http://dx.doi.org/10.1038/s41467-019-09890-8