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Differential human antibody repertoires following Zika infection and the implications for serodiagnostics and disease outcome

Zika virus (ZIKV) outbreak in Americas led to extensive efforts to develop vaccines and ZIKV-specific diagnostics. In the current study, we use whole genome phage display library spanning the entire ZIKV genome (ZIKV-GFPDL) for in-depth immune profiling of IgG and IgM antibody repertoires in serum a...

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Detalles Bibliográficos
Autores principales: Ravichandran, Supriya, Hahn, Megan, Belaunzarán-Zamudio, Pablo F., Ramos-Castañeda, José, Nájera-Cancino, Gabriel, Caballero-Sosa, Sandra, Navarro-Fuentes, Karla R., Ruiz-Palacios, Guillermo, Golding, Hana, Beigel, John H., Khurana, Surender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486612/
https://www.ncbi.nlm.nih.gov/pubmed/31028263
http://dx.doi.org/10.1038/s41467-019-09914-3