Structural basis for RNA translocation by DEAH-box ATPases

DEAH-box adenosine triphosphatases (ATPases) play a crucial role in the spliceosome-mediated excision of pre-mRNA introns. Recent spliceosomal cryo-EM structures suggest that these proteins utilize translocation to apply forces on ssRNAs rather than direct RNA duplex unwinding to ensure global rearr...

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Detalles Bibliográficos
Autores principales: Hamann, Florian, Enders, Marieke, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486627/
https://www.ncbi.nlm.nih.gov/pubmed/30828714
http://dx.doi.org/10.1093/nar/gkz150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486627/
https://www.ncbi.nlm.nih.gov/pubmed/30828714
http://dx.doi.org/10.1093/nar/gkz150

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