Cargando…

Structural basis for RNA translocation by DEAH-box ATPases

DEAH-box adenosine triphosphatases (ATPases) play a crucial role in the spliceosome-mediated excision of pre-mRNA introns. Recent spliceosomal cryo-EM structures suggest that these proteins utilize translocation to apply forces on ssRNAs rather than direct RNA duplex unwinding to ensure global rearr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hamann, Florian, Enders, Marieke, Ficner, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486627/ https://www.ncbi.nlm.nih.gov/pubmed/30828714 http://dx.doi.org/10.1093/nar/gkz150

Ejemplares similares

Crystal structure of the spliceosomal DEAH-box ATPase Prp2
por: Schmitt, Andreas, et al.
Publicado: (2018)

Conformational dynamics of the RNA binding channel regulates loading and translocation of the DEAH-box helicase Prp43
por: Enders, Marieke, et al.
Publicado: (2023)

Regulation of the DEAH/RHA helicase Prp43 by the G-patch factor Pfa1
por: Enders, Marieke, et al.
Publicado: (2022)

The structure of Prp2 bound to RNA and ADP-BeF(3) (−) reveals structural features important for RNA unwinding by DEAH-box ATPases
por: Hamann, Florian, et al.
Publicado: (2021)

Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2
por: Hamann, Florian, et al.
Publicado: (2020)

Structural insights into the mechanism of the DEAH-box RNA helicase Prp43
por: Tauchert, Marcel J, et al.
Publicado: (2017)

Structural basis for m(7)G-cap hypermethylation of small nuclear, small nucleolar and telomerase RNA by the dimethyltransferase TGS1
por: Monecke, Thomas, et al.
Publicado: (2009)

Functional link between DEAH/RHA helicase Prp43 activation and ATP base binding
por: Robert-Paganin, Julien, et al.
Publicado: (2017)

Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase
por: Shi, Wei, et al.
Publicado: (2021)

Structural basis for DEAH-helicase activation by G-patch proteins
por: Studer, Michael K., et al.
Publicado: (2020)

Crystal structure, mutational analysis and RNA-dependent ATPase activity of the yeast DEAD-box pre-mRNA splicing factor Prp28
por: Jacewicz, Agata, et al.
Publicado: (2014)

Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase
por: Li, Zhuo, et al.
Publicado: (2022)

Crystal structure of a 4-thiouridine synthetase–RNA complex reveals specificity of tRNA U8 modification
por: Neumann, Piotr, et al.
Publicado: (2014)

Structural basis of dimerization and dual W-box DNA recognition by rice WRKY domain
por: Cheng, Xiankun, et al.
Publicado: (2019)

Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes
por: Khoshnevis, Sohail, et al.
Publicado: (2014)

Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA
por: He, Yangzi, et al.
Publicado: (2017)

Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor
por: Pajak, Joshua, et al.
Publicado: (2021)

The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction
por: Fourmann, Jean-Baptiste, et al.
Publicado: (2016)

Architecture of the eIF2B regulatory subcomplex and its implications for the regulation of guanine nucleotide exchange on eIF2
por: Kuhle, Bernhard, et al.
Publicado: (2015)

Anti-prion activity of an RNA aptamer and its structural basis
por: Mashima, Tsukasa, et al.
Publicado: (2013)

Structural basis for cloverleaf RNA-initiated viral genome replication
por: Gottipati, Keerthi, et al.
Publicado: (2023)

Structure and function of DEAH-box helicase 32 and its role in cancer
por: Wei, Qingchun, et al.
Publicado: (2021)

Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase
por: Ito, Kosuke, et al.
Publicado: (2012)

Structural basis for the specific recognition of 18S rRNA by APUM23
por: Bao, Hongyu, et al.
Publicado: (2017)

Structural basis for the selective methylation of 5-carboxymethoxyuridine in tRNA modification
por: Yoo, Jaehun, et al.
Publicado: (2023)

Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase
por: Tian, Qingnan, et al.
Publicado: (2015)

Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis
por: Majumdar, Soneya, et al.
Publicado: (2023)

Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction
por: Westblade, Lars F., et al.
Publicado: (2010)

Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1
por: Montemayor, Eric J., et al.
Publicado: (2014)

Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers
por: Kuhlmann, Sonja I., et al.
Publicado: (2014)

Structural basis for single-stranded RNA recognition and cleavage by C3PO
por: Zhang, Jing, et al.
Publicado: (2016)

Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ
por: Huang, Jie, et al.
Publicado: (2020)

Structural basis of UCUU RNA motif recognition by splicing factor RBM20
por: Upadhyay, Santosh Kumar, et al.
Publicado: (2020)

Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei
por: Gao, Yanqing, et al.
Publicado: (2020)

Structural basis of 3′-end poly(A) RNA recognition by LARP1
por: Kozlov, Guennadi, et al.
Publicado: (2022)

Structural basis for guide RNA selection by the RESC1–RESC2 complex
por: Dolce, Luciano G, et al.
Publicado: (2023)

Structures of the T. brucei kRNA editing factor MRB1590 reveal unique RNA-binding pore motif contained within an ABC-ATPase fold
por: Shaw, Porsha L. R., et al.
Publicado: (2015)

Structural basis of σ appropriation
por: Shi, Jing, et al.
Publicado: (2019)

Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms
por: Tsunoda, Masaru, et al.
Publicado: (2007)

Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes
por: Kim, Dong Kyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_06mr3of4t4upjflsjvtt205lcf