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Enzyme-free ligation of dimers and trimers to RNA primers

The template-directed formation of phosphodiester bonds between two nucleic acid components is a pivotal process in biology. To induce such a reaction in the absence of enzymes is a challenge. This challenge has been met for the extension of a primer with mononucleotides, but the ligation of short o...

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Detalles Bibliográficos
Autores principales: Sosson, Marilyne, Pfeffer, Daniel, Richert, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486630/
https://www.ncbi.nlm.nih.gov/pubmed/30869145
http://dx.doi.org/10.1093/nar/gkz160