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Accurate high throughput alignment via line sweep-based seed processing

Accurate and fast aligners are required to handle the steadily increasing volume of sequencing data. Here we present an approach allowing performant alignments of short reads (Illumina) as well as long reads (Pacific Bioscience, Ultralong Oxford Nanopore), while achieving high accuracy, based on a u...

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Detalles Bibliográficos
Autores principales: Schmidt, Markus, Heese, Klaus, Kutzner, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486643/
https://www.ncbi.nlm.nih.gov/pubmed/31028275
http://dx.doi.org/10.1038/s41467-019-09977-2