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Accurate high throughput alignment via line sweep-based seed processing
Accurate and fast aligners are required to handle the steadily increasing volume of sequencing data. Here we present an approach allowing performant alignments of short reads (Illumina) as well as long reads (Pacific Bioscience, Ultralong Oxford Nanopore), while achieving high accuracy, based on a u...
Autores principales: | Schmidt, Markus, Heese, Klaus, Kutzner, Arne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486643/ https://www.ncbi.nlm.nih.gov/pubmed/31028275 http://dx.doi.org/10.1038/s41467-019-09977-2 |
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