Mechanism mediated by a noncoding RNA, nc886, in the cytotoxicity of a DNA-reactive compound

DNA-reactive compounds are harnessed for cancer chemotherapy. Their genotoxic effects are considered to be the main mechanism for the cytotoxicity to date. Because this mechanism preferentially affects actively proliferating cells, it is postulated that the cytotoxicity is specific to cancer cells....

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Detalles Bibliográficos
Autores principales: Kunkeaw, Nawapol, Lee, Yeon-Su, Im, Wonkyun Ronny, Jang, Jiyoung Joan, Song, Min-Ji, Yang, Bobae, Park, Jong-Lyul, Kim, Seon-Young, Ku, Yongsuk, Kim, Yoosik, Kang, Sangmin, Jo, Hye-ram, Jeong, Jae-Hoon, Lee, Hyun-Sung, Lee, Ju-Seog, Kim, Hyoung-Pyo, Johnson, Betty H., Kim, In-Hoo, Lee, Yong Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486756/
https://www.ncbi.nlm.nih.gov/pubmed/30948645
http://dx.doi.org/10.1073/pnas.1814510116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486756/
https://www.ncbi.nlm.nih.gov/pubmed/30948645
http://dx.doi.org/10.1073/pnas.1814510116

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