The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation

BAF complexes are composed of different subunits with varying functional and developmental roles, although many subunits have not been examined in depth. Here we show that the Baf45 subunit Dpf2 maintains pluripotency and ESC differentiation potential. Dpf2 co-occupies enhancers with Oct4, Sox2, p30...

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Detalles Bibliográficos
Autores principales: Zhang, Wensheng, Chronis, Constantinos, Chen, Xi, Zhang, Heyao, Spalinskas, Rapolas, Pardo, Mercedes, Chen, Liangliang, Wu, Guangming, Zhu, Zhexin, Yu, Yong, Yu, Lu, Choudhary, Jyoti, Nichols, Jennifer, Parast, Mana M., Greber, Boris, Sahlén, Pelin, Plath, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486830/
https://www.ncbi.nlm.nih.gov/pubmed/30609396
http://dx.doi.org/10.1016/j.stem.2018.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486830/
https://www.ncbi.nlm.nih.gov/pubmed/30609396
http://dx.doi.org/10.1016/j.stem.2018.12.001

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