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Replication of the pharmacogenetic effect of rs678849 on buprenorphine efficacy in African-Americans with opioid use disorder

Many patients with opioid use disorder do not have successful outcomes during treatment but the underlying reasons are not well understood. An OPRD1 variant (rs678849) was previously associated with methadone and buprenorphine efficacy in African-Americans with opioid use disorder. The objective of...

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Detalles Bibliográficos
Autores principales: Crist*, Richard. C., Phillips, Karran. A., Furnari, Melody. A., Moran, Landhing. M., Doyle, Glenn. A., McNicholas, Laura. F., Cornish, James. W., Kampman, Kyle. M., Preston, Kenzie. L., Berrettini, Wade. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486881/
https://www.ncbi.nlm.nih.gov/pubmed/30368523
http://dx.doi.org/10.1038/s41397-018-0065-x