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Immunoglobulin G responses against falciparum malaria specific antigens are higher in children with homozygous sickle cell trait than those with normal hemoglobin

BACKGROUND: High Immunoglobulin G (IgG) response to Plasmodium falciparum antigens is associated with partial malaria protection in sickle hemoglobin (HbS) children. However, this response has been more studied in children with heterozygous sickle cell trait (HbAS) but little explored in those with...

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Detalles Bibliográficos
Autores principales: Bwire, George Msema, Majigo, Mtebe, Makalla, Robert, Nkinda, Lillian, Mawazo, Akili, Mizinduko, Mucho, Makani, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486967/
https://www.ncbi.nlm.nih.gov/pubmed/31029083
http://dx.doi.org/10.1186/s12865-019-0294-z