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Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines

BACKGROUND: Transposable elements (TE) are commonly regarded as “junk DNA” with no apparent regulatory roles in the human genome. However, a growing body of evidence demonstrates that some TEs exhibit regulatory activities in a range of biological pathways and diseases, with notable examples in bile...

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Detalles Bibliográficos
Autores principales: Jiang, Jiayue-Clara, Upton, Kyle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486989/
https://www.ncbi.nlm.nih.gov/pubmed/31061680
http://dx.doi.org/10.1186/s13100-019-0158-3