Cargando…
Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines
BACKGROUND: Transposable elements (TE) are commonly regarded as “junk DNA” with no apparent regulatory roles in the human genome. However, a growing body of evidence demonstrates that some TEs exhibit regulatory activities in a range of biological pathways and diseases, with notable examples in bile...
Autores principales: | Jiang, Jiayue-Clara, Upton, Kyle R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486989/ https://www.ncbi.nlm.nih.gov/pubmed/31061680 http://dx.doi.org/10.1186/s13100-019-0158-3 |
Ejemplares similares
-
Widespread Exaptation of L1 Transposons for Transcription Factor Binding in Breast Cancer
por: Jiang, Jiayue-Clara, et al.
Publicado: (2021) -
Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model
por: Jiang, Jiayue-Clara, et al.
Publicado: (2021) -
P53 Binding Sites in Transposons
por: Zemojtel, Tomasz, et al.
Publicado: (2012) -
De-Novo Discovery of Differentially Abundant Transcription Factor Binding Sites Including Their Positional Preference
por: Keilwagen, Jens, et al.
Publicado: (2011) -
Evaluation of the Abundance of DNA-Binding Transcription Factors in Prokaryotes
por: Sanchez, Israel, et al.
Publicado: (2020)