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Paracrine effects of CCN3 from non-cancerous hepatic cells increase signaling and progression of hepatocellular carcinoma

BACKGROUND: The liver microenvironment plays a key role in the progression and metastasis of hepatocellular carcinoma (HCC). Gene expression profiling of non-cancerous hepatic tissues obtained from patients with metastatic HCC exhibit a unique immune response signature, including upregulation of CCN...

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Detalles Bibliográficos
Autores principales: Li, Weimin, Liao, Xia, Ning, Pengbo, Cao, Yu, Zhang, Mei, Bu, Yang, Lv, Jun, Jia, Qingan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486990/
https://www.ncbi.nlm.nih.gov/pubmed/31029128
http://dx.doi.org/10.1186/s12885-019-5603-7