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MiR-200c downregulates HIF-1α and inhibits migration of lung cancer cells

BACKGROUND: Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor with a pivotal role in physiological and pathological responses to hypoxia. While HIF-1α is known to be involved in hypoxia-induced upregulation of microRNA (miRNA) expression, HIF-1α is also targeted by miRNAs. In this study...

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Detalles Bibliográficos
Autores principales: Byun, Yuree, Choi, Young-Chul, Jeong, Yunhui, Lee, Gangtae, Yoon, Sena, Jeong, Yongsu, Yoon, Jaeseung, Baek, Kwanghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487019/
https://www.ncbi.nlm.nih.gov/pubmed/31061665
http://dx.doi.org/10.1186/s11658-019-0152-2