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RIPK1 suppresses apoptosis mediated by TNF and caspase-3 in intervertebral discs

BACKGROUND: Low back pain has become a serious social and economic burden and the leading cause of disability worldwide. Among a variety of pathophysiological triggers, intervertebral disc (IVD) degeneration plays a primary underlying role in causing such pain. Specifically, multiple independent end...

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Detalles Bibliográficos
Autores principales: Qiu, Xubin, Zhuang, Ming, Lu, Ziwen, Liu, Zhiwei, Cheng, Dong, Zhu, Chenlei, Liu, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487042/
https://www.ncbi.nlm.nih.gov/pubmed/31029152
http://dx.doi.org/10.1186/s12967-019-1886-3