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RIPK1 suppresses apoptosis mediated by TNF and caspase-3 in intervertebral discs
BACKGROUND: Low back pain has become a serious social and economic burden and the leading cause of disability worldwide. Among a variety of pathophysiological triggers, intervertebral disc (IVD) degeneration plays a primary underlying role in causing such pain. Specifically, multiple independent end...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487042/ https://www.ncbi.nlm.nih.gov/pubmed/31029152 http://dx.doi.org/10.1186/s12967-019-1886-3 |