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Potential Applications of NRF2 Inhibitors in Cancer Therapy

The NRF2/KEAP1 pathway represents one of the most important cell defense mechanisms against exogenous or endogenous stressors. Indeed, by increasing the expression of several cytoprotective genes, the transcription factor NRF2 can shelter cells and tissues from multiple sources of damage including x...

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Detalles Bibliográficos
Autores principales: Panieri, Emiliano, Saso, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487091/
https://www.ncbi.nlm.nih.gov/pubmed/31097977
http://dx.doi.org/10.1155/2019/8592348