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Melatonin Increases Bone Mass around the Prostheses of OVX Rats by Ameliorating Mitochondrial Oxidative Stress via the SIRT3/SOD2 Signaling Pathway

Bone mass loss around prostheses is a major cause of implant failure, especially in postmenopausal osteoporosis patients. In osteoporosis, excess oxidative stress largely contributed abnormal bone remodeling. Melatonin, which is synthesized from the pineal gland, promotes osteoblast differentiation...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Liu, Yu, Shen, Jining, Yu, Binqing, Bai, Jiaxiang, Lin, Jiayi, Guo, Xiaobin, Sun, Houyi, Chen, Zhanghuan, Yang, Huilin, Xu, Yaozeng, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487111/
https://www.ncbi.nlm.nih.gov/pubmed/31110599
http://dx.doi.org/10.1155/2019/4019619