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Fluoxetine suppresses inflammatory reaction in microglia under OGD/R challenge via modulation of NF-κB signaling

We aimed to investigate the anti-inflammatory role of fluoxetine, a selective serotonin reuptake inhibitor, in microglia (MG) and the mechanisms under oxygen glucose deprivation/reoxygenation (OGD/R). An OGD/R model on BV-2 cells was used for the study of microglia under ischemia/reperfusion injury...

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Detalles Bibliográficos
Autores principales: Tian, Mouli, Yang, Mei, Li, Zhenjie, Wang, Yiru, Chen, Wei, Yang, Liye, Li, Yonghua, Yuan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487262/
https://www.ncbi.nlm.nih.gov/pubmed/30944203
http://dx.doi.org/10.1042/BSR20181584