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Kinetic and structural analysis of human ALDH9A1

Aldehyde dehydrogenases (ALDHs) constitute a superfamily of NAD(P)(+)-dependent enzymes, which detoxify aldehydes produced in various metabolic pathways to the corresponding carboxylic acids. Among the 19 human ALDHs, the cytosolic ALDH9A1 has so far never been fully enzymatically characterized and...

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Detalles Bibliográficos
Autores principales: Končitíková, Radka, Vigouroux, Armelle, Kopečná, Martina, Šebela, Marek, Moréra, Solange, Kopečný, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487263/
https://www.ncbi.nlm.nih.gov/pubmed/30914451
http://dx.doi.org/10.1042/BSR20190558