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Parathyroid hormone-related protein induces fibronectin up-regulation in rat mesangial cells through reactive oxygen species/Src/EGFR signaling

Parathyroid hormone-related protein (PTHrP) is known to be up-regulated in both glomeruli and tubules in patients with diabetic kidney disease (DKD), but its role remains unclear. Previous studies show that PTHrP-induced hypertrophic response in mesangial cells (MCs) and epithelial-mesenchymal trans...

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Detalles Bibliográficos
Autores principales: Chen, Hong-Min, Dai, Jia-Jia, Zhu, Rui, Peng, Fang-Fang, Wu, Su-Zhen, Yu, Hong, Krepinsky, Joan C., Zhang, Bai-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487264/
https://www.ncbi.nlm.nih.gov/pubmed/30926678
http://dx.doi.org/10.1042/BSR20182293