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Parathyroid hormone-related protein induces fibronectin up-regulation in rat mesangial cells through reactive oxygen species/Src/EGFR signaling
Parathyroid hormone-related protein (PTHrP) is known to be up-regulated in both glomeruli and tubules in patients with diabetic kidney disease (DKD), but its role remains unclear. Previous studies show that PTHrP-induced hypertrophic response in mesangial cells (MCs) and epithelial-mesenchymal trans...
Autores principales: | Chen, Hong-Min, Dai, Jia-Jia, Zhu, Rui, Peng, Fang-Fang, Wu, Su-Zhen, Yu, Hong, Krepinsky, Joan C., Zhang, Bai-Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487264/ https://www.ncbi.nlm.nih.gov/pubmed/30926678 http://dx.doi.org/10.1042/BSR20182293 |
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