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Validation of a cell-based colorimetric reporter gene assay for the evaluation of Type I Interferons

The biotherapeutic type I interferons (IFN-I) are indicated to treat several diseases. These products are regulated to guarantee safety and efficacy through critical quality attributes. For this purpose, the development of robust assays is required, followed by its validation to demonstrate their su...

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Detalles Bibliográficos
Autores principales: Mejía-Calvo, Ignacio, Muñoz-García, Leslie, Jiménez-Uribe, Alexis, Camacho-Sandoval, Rosa, González-González, Edith, Mellado-Sánchez, Gabriela, Tenorio-Calvo, Alejandra V., López-Morales, Carlos A., Velasco-Velázquez, Marco A., Pavón, Lenin, Pérez-Tapia, Sonia Mayra, Medina-Rivero, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487280/
https://www.ncbi.nlm.nih.gov/pubmed/31061815
http://dx.doi.org/10.1016/j.btre.2019.e00331