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Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes
In 2004, a subclinical case of variant Creutzfeldt-Jakob disease in a PRNP 129 methionine/valine heterozygous individual infected via blood transfusion was reported, and we established that the spleen from this individual was infectious. Since host genetics is an important factor in strain modificat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487331/ https://www.ncbi.nlm.nih.gov/pubmed/30938429 http://dx.doi.org/10.1093/brain/awz076 |