Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes

In 2004, a subclinical case of variant Creutzfeldt-Jakob disease in a PRNP 129 methionine/valine heterozygous individual infected via blood transfusion was reported, and we established that the spleen from this individual was infectious. Since host genetics is an important factor in strain modificat...

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Detalles Bibliográficos
Autores principales: Diack, Abigail B, Boyle, Aileen, Plinston, Christopher, Hunt, Emma, Bishop, Matthew T, Will, Robert G, Manson, Jean C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487331/
https://www.ncbi.nlm.nih.gov/pubmed/30938429
http://dx.doi.org/10.1093/brain/awz076

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