Reactivation of nonsense-mediated mRNA decay protects against C9orf72 dipeptide-repeat neurotoxicity

Amyotrophic lateral sclerosis is a deleterious neurodegenerative disease without effective treatment options. Recent studies have indicated the involvement of the dysregulation of RNA metabolism in the pathogenesis of amyotrophic lateral sclerosis. Among the various RNA regulatory machineries, nonse...

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Detalles Bibliográficos
Autores principales: Xu, Wangchao, Bao, Puhua, Jiang, Xin, Wang, Haifang, Qin, Meiling, Wang, Ruiqi, Wang, Tao, Yang, Yi, Lorenzini, Ileana, Liao, Lujian, Sattler, Rita, Xu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487333/
https://www.ncbi.nlm.nih.gov/pubmed/30938419
http://dx.doi.org/10.1093/brain/awz070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487333/
https://www.ncbi.nlm.nih.gov/pubmed/30938419
http://dx.doi.org/10.1093/brain/awz070

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