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Clostridium perfringens Epsilon Toxin Compromises the Blood-Brain Barrier in a Humanized Zebrafish Model

Clostridium perfringens epsilon toxin (ETX) is hypothesized to mediate blood-brain barrier (BBB) permeability by binding to the myelin and lymphocyte protein (MAL) on the luminal surface of endothelial cells (ECs). However, the kinetics of this interaction and a general understanding of ETX's b...

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Detalles Bibliográficos
Autores principales: Adler, Drew, Linden, Jennifer R., Shetty, Samantha V., Ma, Yinghua, Bokori-Brown, Monika, Titball, Richard W., Vartanian, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487375/
https://www.ncbi.nlm.nih.gov/pubmed/31030181
http://dx.doi.org/10.1016/j.isci.2019.04.016