Loss of GCN5L1 in cardiac cells limits mitochondrial respiratory capacity under hyperglycemic conditions

The mitochondrial acetyltransferase‐related protein GCN5L1 controls the activity of fuel substrate metabolism enzymes in several tissues. While previous studies have demonstrated that GCN5L1 regulates fatty acid oxidation in the prediabetic heart, our understanding of its role in overt diabetes is n...

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Detalles Bibliográficos
Autores principales: Thapa, Dharendra, Zhang, Manling, Manning, Janet R., Guimarães, Danielle A., Stoner, Michael W., Lai, Yen‐Chun, Shiva, Sruti, Scott, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487468/
https://www.ncbi.nlm.nih.gov/pubmed/31033247
http://dx.doi.org/10.14814/phy2.14054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487468/
https://www.ncbi.nlm.nih.gov/pubmed/31033247
http://dx.doi.org/10.14814/phy2.14054

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