Sickle cell disease up‐regulates vasopressin, aquaporin 2, urea transporter A1, Na‐K‐Cl cotransporter 2, and epithelial Na channels in the mouse kidney medulla despite compromising urinary concentration ability

Sickle cell disease (SCD)‐induced urinary concentration defect has been proposed as caused by impaired ability of the occluded vasa recta due to red blood cell sickling to serve as countercurrent exchangers and renal tubules to absorb water and solutes. However, the exact molecular mechanisms remain...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Morris, Ryan G., Knepper, Mark A., Zhou, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487471/
https://www.ncbi.nlm.nih.gov/pubmed/31033226
http://dx.doi.org/10.14814/phy2.14066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487471/
https://www.ncbi.nlm.nih.gov/pubmed/31033226
http://dx.doi.org/10.14814/phy2.14066

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