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A common SNP in the UNG gene decreases ovarian cancer risk in BRCA2 mutation carriers

Single nucleotide polymorphisms (SNPs) in DNA glycosylase genes involved in the base excision repair (BER) pathway can modify breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. We previously found that SNP rs34259 in the uracil‐DNA glycosylase gene (UNG) might decrease ovarian canc...

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Detalles Bibliográficos
Autores principales: Baquero, Juan Miguel, Benítez‐Buelga, Carlos, Fernández, Victoria, Urioste, Miguel, García‐Giménez, Jose Luis, Perona, Rosario, Benítez, Javier, Osorio, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487686/
https://www.ncbi.nlm.nih.gov/pubmed/30747491
http://dx.doi.org/10.1002/1878-0261.12470