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The strong propensity of Cadherin‐23 for aggregation inhibits cell migration

Cadherin‐23 (Cdh23), a long‐chain non‐classical cadherin, exhibits strong homophilic and heterophilic binding. The physiological relevance of strong heterophilic binding with protocadherin‐15 at neuroepithelial tip links is well‐studied. However, the role of Cdh23 homodimers in physiology is less un...

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Detalles Bibliográficos
Autores principales: Sannigrahi, Malay K., Srinivas, Cheerneni S., Deokate, Nilesh, Rakshit, Sabyasachi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487693/
https://www.ncbi.nlm.nih.gov/pubmed/30747484
http://dx.doi.org/10.1002/1878-0261.12469