Inhibition of glycolysis disrupts cellular antioxidant defense and sensitizes HepG2 cells to doxorubicin treatment

Increased glucose consumption is a known hallmark of cancer cells. Increased glycolysis provides ATP, reducing agents and substrates for macromolecular synthesis in intensely dividing cells. Therefore, inhibition of glycolysis is one strategy in anticancer therapy as well as in improved efficacy of...

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Detalles Bibliográficos
Autores principales: Korga, Agnieszka, Ostrowska, Marta, Iwan, Magdalena, Herbet, Mariola, Dudka, Jaroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487699/
https://www.ncbi.nlm.nih.gov/pubmed/30973680
http://dx.doi.org/10.1002/2211-5463.12628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487699/
https://www.ncbi.nlm.nih.gov/pubmed/30973680
http://dx.doi.org/10.1002/2211-5463.12628

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