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Identification of a peptide antagonist of the FGF1–FGFR1 signaling axis by phage display selection

Overexpression of fibroblast growth factor receptor 1 (FGFR1) is a common aberration in lung and breast cancers and has necessitated the design of drugs targeting FGFR1‐dependent downstream signaling and FGFR1 ligand binding. To date, the major group of drugs being developed for treatment of FGFR1‐d...

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Detalles Bibliográficos
Autores principales: Lipok, Magdalena, Szlachcic, Anna, Kindela, Kinga, Czyrek, Aleksandra, Otlewski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487701/
https://www.ncbi.nlm.nih.gov/pubmed/30968602
http://dx.doi.org/10.1002/2211-5463.12618