Human aldehyde oxidase (hAOX1): structure determination of the Moco‐free form of the natural variant G1269R and biophysical studies of single nucleotide polymorphisms

Human aldehyde oxidase (hAOX1) is a molybdenum enzyme with high toxicological importance, but its physiological role is still unknown. hAOX1 metabolizes different classes of xenobiotics and is one of the main drug‐metabolizing enzymes in the liver, along with cytochrome P450. hAOX1 oxidizes and inac...

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Detalles Bibliográficos
Autores principales: Mota, Cristiano, Esmaeeli, Mariam, Coelho, Catarina, Santos‐Silva, Teresa, Wolff, Martin, Foti, Alessandro, Leimkühler, Silke, Romão, Maria João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487702/
https://www.ncbi.nlm.nih.gov/pubmed/30985987
http://dx.doi.org/10.1002/2211-5463.12617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487702/
https://www.ncbi.nlm.nih.gov/pubmed/30985987
http://dx.doi.org/10.1002/2211-5463.12617

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