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PTPRK suppresses progression and chemo‐resistance of colon cancer cells via direct inhibition of pro‐oncogenic CD133

Receptor‐type protein tyrosine phosphatase κ (PTPRK) is considered to be a candidate tumor suppressor. PTPRK dephosphorylates CD133, which is a stem cell marker; phosphorylated CD133 accelerates xenograft tumor growth of colon cancer cells through the activation of AKT, but the functional significan...

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Detalles Bibliográficos
Autores principales:	Matsushita, Masashi, Mori, Yusuke, Uchiumi, Kyosuke, Ogata, Takehiro, Nakamura, Mizuyo, Yoda, Hiroyuki, Soda, Hiroaki, Takiguchi, Nobuhiro, Nabeya, Yoshihiro, Shimozato, Osamu, Ozaki, Toshinori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487712/ https://www.ncbi.nlm.nih.gov/pubmed/30947381 http://dx.doi.org/10.1002/2211-5463.12636

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