Memantine selectively prevented the induction of dynamic allodynia by blocking Kir2.1 channel and inhibiting the activation of microglia in spinal dorsal horn of mice in spared nerve injury model

BACKGROUND: Memantine is one of the important clinical medications in treating moderate to severe Alzheimer disease. The effect of memantine on preventing or treating punctate allodynia has been thoroughly studied but not on the induction of dynamic allodynia. The aim of this study is to investigate...

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Detalles Bibliográficos
Autores principales: Chen, Yangyang, Shi, Yiqian, Wang, Guoxiang, Li, Yimei, Cheng, Longzhen, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487752/
https://www.ncbi.nlm.nih.gov/pubmed/30845882
http://dx.doi.org/10.1177/1744806919838947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487752/
https://www.ncbi.nlm.nih.gov/pubmed/30845882
http://dx.doi.org/10.1177/1744806919838947

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