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Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting
The transcription factor p53 plays pivotal roles in numerous biological processes, including the suppression of tumours. The rich availability of biophysical data aimed at understanding its structure–function relationships since the 1990s has enabled the application of a variety of computational mod...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487789/ https://www.ncbi.nlm.nih.gov/pubmed/30726928 http://dx.doi.org/10.1093/jmcb/mjz009 |