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A combination of curcumin, vorinostat and silibinin reverses Aβ-induced nerve cell toxicity via activation of AKT-MDM2-p53 pathway

Alzheimer’s disease (AD) is a significant health issue for the elderly and becoming increasingly common as the global population ages. Although many efforts have been made to elucidate its pathology, there is still a lack of effective clinical anti-AD agents. Previous research has shown the neuropro...

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Detalles Bibliográficos
Autores principales: Meng, Jia, Li, Yan, Zhang, Mingming, Li, Wenjing, Zhou, Lin, Wang, Qiujun, Lin, Lin, Jiang, Lihong, Zhu, Wenliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487801/
https://www.ncbi.nlm.nih.gov/pubmed/31086728
http://dx.doi.org/10.7717/peerj.6716