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A combination of curcumin, vorinostat and silibinin reverses Aβ-induced nerve cell toxicity via activation of AKT-MDM2-p53 pathway
Alzheimer’s disease (AD) is a significant health issue for the elderly and becoming increasingly common as the global population ages. Although many efforts have been made to elucidate its pathology, there is still a lack of effective clinical anti-AD agents. Previous research has shown the neuropro...
Autores principales: | Meng, Jia, Li, Yan, Zhang, Mingming, Li, Wenjing, Zhou, Lin, Wang, Qiujun, Lin, Lin, Jiang, Lihong, Zhu, Wenliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487801/ https://www.ncbi.nlm.nih.gov/pubmed/31086728 http://dx.doi.org/10.7717/peerj.6716 |
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