Behavioral flexibility in a mouse model for obsessive‐compulsive disorder: Impaired Pavlovian reversal learning in SAPAP3 mutants

Obsessive‐compulsive disorder (OCD) is characterized by obsessive thinking, compulsive behavior and anxiety, and is often accompanied by cognitive deficits. The neuropathology of OCD involves dysregulation of cortical‐striatal circuits. Similar to OCD patients, SAPAP3 knockout mice 3 (SAPAP3(−/−)) e...

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Detalles Bibliográficos
Autores principales: van den Boom, Bastijn J.G., Mooij, Adriana H., Misevičiūtė, Ieva, Denys, Damiaan, Willuhn, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487954/
https://www.ncbi.nlm.nih.gov/pubmed/30688005
http://dx.doi.org/10.1111/gbb.12557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487954/
https://www.ncbi.nlm.nih.gov/pubmed/30688005
http://dx.doi.org/10.1111/gbb.12557

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