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Behavioral flexibility in a mouse model for obsessive‐compulsive disorder: Impaired Pavlovian reversal learning in SAPAP3 mutants
Obsessive‐compulsive disorder (OCD) is characterized by obsessive thinking, compulsive behavior and anxiety, and is often accompanied by cognitive deficits. The neuropathology of OCD involves dysregulation of cortical‐striatal circuits. Similar to OCD patients, SAPAP3 knockout mice 3 (SAPAP3(−/−)) e...
Autores principales: | van den Boom, Bastijn J.G., Mooij, Adriana H., Misevičiūtė, Ieva, Denys, Damiaan, Willuhn, Ingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487954/ https://www.ncbi.nlm.nih.gov/pubmed/30688005 http://dx.doi.org/10.1111/gbb.12557 |
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