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Global Proteomic and Methylome Analysis in Human Induced Pluripotent Stem Cells Reveals Overexpression of a Human TLR3 Affecting Proper Innate Immune Response Signaling

When considering the clinical applications of autologous cell replacement therapy of human induced pluripotent stem cells (iPSC)‐derived cells, there is a clear need to better understand what the immune response will be before we embark on extensive clinical trials to treat or model human disease. W...

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Detalles Bibliográficos
Autores principales: Requena, Jordi, Alvarez‐Palomo, Ana Belen, Codina‐Pascual, Montserrat, Delgado‐Morales, Raul, Moran, Sebastian, Esteller, Manel, Sal, Martí, Juan, Manel, Boronat Barado, Anna, Consiglio, Antonella, Bogle, Orleigh Addeleccia, Wolvetang, Ernst, Ovchinnikov, Dmitry, Alvarez, Inaki, Jaraquemada, Dolores, Mezquita‐Pla, Jovita, Oliva, Rafael, Edel, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487958/
https://www.ncbi.nlm.nih.gov/pubmed/30664289
http://dx.doi.org/10.1002/stem.2966