Streptococcal dTDP‐L‐rhamnose biosynthesis enzymes: functional characterization and lead compound identification

Biosynthesis of the nucleotide sugar precursor dTDP‐L‐rhamnose is critical for the viability and virulence of many human pathogenic bacteria, including Streptococcus pyogenes (Group A Streptococcus; GAS), Streptococcus mutans and Mycobacterium tuberculosis. Streptococcal pathogens require dTDP‐L‐rha...

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Detalles Bibliográficos
Autores principales: van der Beek, Samantha L., Zorzoli, Azul, Çanak, Ebru, Chapman, Robert N., Lucas, Kieron, Meyer, Benjamin H., Evangelopoulos, Dimitrios, de Carvalho, Luiz Pedro S., Boons, Geert‐Jan, Dorfmueller, Helge C., van Sorge, Nina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487966/
https://www.ncbi.nlm.nih.gov/pubmed/30600561
http://dx.doi.org/10.1111/mmi.14197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487966/
https://www.ncbi.nlm.nih.gov/pubmed/30600561
http://dx.doi.org/10.1111/mmi.14197

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