Flow-enhanced vascularization and maturation of kidney organoids in vitro

Kidney organoids derived from human pluripotent stem cells exhibit glomerular- and tubular-like compartments that are largely avascular and immature in static culture. Here, we report an in vitro method for culturing kidney organoids under flow on millifluidic chips, which greatly expands their endo...

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Detalles Bibliográficos
Autores principales: Homan, Kimberly A., Gupta, Navin, Kroll, Katharina T., Kolesky, David B., Skylar-Scott, Mark, Miyoshi, Tomoya, Mau, Donald, Valerius, M. Todd, Ferrante, Thomas, Bonventre, Joseph V., Lewis, Jennifer A., Morizane, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488032/
https://www.ncbi.nlm.nih.gov/pubmed/30742039
http://dx.doi.org/10.1038/s41592-019-0325-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488032/
https://www.ncbi.nlm.nih.gov/pubmed/30742039
http://dx.doi.org/10.1038/s41592-019-0325-y

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