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Flow-enhanced vascularization and maturation of kidney organoids in vitro
Kidney organoids derived from human pluripotent stem cells exhibit glomerular- and tubular-like compartments that are largely avascular and immature in static culture. Here, we report an in vitro method for culturing kidney organoids under flow on millifluidic chips, which greatly expands their endo...
Autores principales: | Homan, Kimberly A., Gupta, Navin, Kroll, Katharina T., Kolesky, David B., Skylar-Scott, Mark, Miyoshi, Tomoya, Mau, Donald, Valerius, M. Todd, Ferrante, Thomas, Bonventre, Joseph V., Lewis, Jennifer A., Morizane, Ryuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488032/ https://www.ncbi.nlm.nih.gov/pubmed/30742039 http://dx.doi.org/10.1038/s41592-019-0325-y |
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