The conservation and functionality of the oxygen-sensing enzyme Factor Inhibiting HIF (FIH) in non-vertebrates

The asparaginyl hydroxylase, Factor Inhibiting HIF (FIH), is a cellular dioxygenase. Originally identified as oxygen sensor in the cellular response to hypoxia, where FIH acts as a repressor of the hypoxia inducible transcription factor alpha (HIF-α) proteins through asparaginyl hydroxylation, FIH a...

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Detalles Bibliográficos
Autores principales: Hampton-Smith, Rachel J., Davenport, Briony A., Nagarajan, Yagnesh, Peet, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488082/
https://www.ncbi.nlm.nih.gov/pubmed/31034531
http://dx.doi.org/10.1371/journal.pone.0216134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488082/
https://www.ncbi.nlm.nih.gov/pubmed/31034531
http://dx.doi.org/10.1371/journal.pone.0216134

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