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Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease

Chagas Disease (CD) is an anthropozoonosis caused by Trypanosoma cruzi. With complex pathophysiology and variable clinical presentation, CD outcome can be influenced by parasite persistence and the host immune response. Complement activation is one of the primary defense mechanisms against pathogens...

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Detalles Bibliográficos
Autores principales: Sandri, Thaisa Lucas, Andrade, Fabiana Antunes, Lidani, Kárita Cláudia Freitas, Einig, Elias, Boldt, Angelica Beate Winter, Mordmüller, Benjamin, Esen, Meral, Messias-Reason, Iara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488100/
https://www.ncbi.nlm.nih.gov/pubmed/30995222
http://dx.doi.org/10.1371/journal.pntd.0007324