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Whole body glucoregulation and tissue-specific glucose uptake in a novel Akt substrate of 160 kDa knockout rat model

Akt substrate of 160 kDa (also called AS160 or TBC1D4) is a Rab GTPase activating protein and key regulator of insulin-stimulated glucose uptake which is expressed by multiple tissues, including skeletal muscle, white adipose tissue (WAT) and the heart. This study introduces a novel rat AS160-knocko...

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Detalles Bibliográficos
Autores principales: Arias, Edward B., Zheng, Xiaohua, Agrawal, Swati, Cartee, Gregory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488193/
https://www.ncbi.nlm.nih.gov/pubmed/31034517
http://dx.doi.org/10.1371/journal.pone.0216236