Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency

During early mammalian development, the chromatin landscape undergoes profound transitions. The Zdbf2 gene—involved in growth control—provides a valuable model to study this window: upon exit from naïve pluripotency and prior to tissue differentiation, it undergoes a switch from a distal to a proxim...

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Detalles Bibliográficos
Autores principales: Greenberg, Maxim, Teissandier, Aurélie, Walter, Marius, Noordermeer, Daan, Bourc'his, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488298/
https://www.ncbi.nlm.nih.gov/pubmed/30990414
http://dx.doi.org/10.7554/eLife.44057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488298/
https://www.ncbi.nlm.nih.gov/pubmed/30990414
http://dx.doi.org/10.7554/eLife.44057

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